Differential responses of neuronal and spermatogenic cells to the doppel cytotoxicity.
Although structurally and biochemically similar to the cellular prion (PrP(C)), doppel (Dpl) is unique in its biological functions.There are no wes audio 1176 reports about any neurodegenerative diseases induced by Dpl.However the artificial expression of Dpl in the PrP-deficient mouse brain causes ataxia with Purkinje cell death.Abundant Dpl prote